The early death of their parents forced Elaine (Christina Ritchie Christina Ricci) and Jim (Jesse Eisenberg Jesse Eisenberg) to lead a miserable life of mutual dependence, but even so, their bad relationship hasn't changed at all. In an accident, brother and sister were in a car accident, but fortunately it was all right, but what happened next was not so lucky-they were attacked by a huge wolf. Although they were injured, Elaine and Jim at least saved their lives, but since the day of the attack, some changes that they can't ignore have begun to take place in them, their senses have become extremely sensitive, their skin has grown rough hair, their character has begun to change, and everything points to an answer-Elaine and Jim have begun to mutate into werewolves.