Pitt (Jason Siegel Jason Segel) is a musician with a much better girlfriend, Sarah Marshall (Christine Bell Kristen Bell), who is a popular TV star. Peter was obsessed with her, but he was abandoned by her. After a long period of depression and watching all kinds of news about Sarah on TV, the battered Pitt went on vacation in Honolulu, Hawaii, only to meet Sarah and her new boyfriend in a hotel. Pitt feels that fate is playing a trick on him, but then he meets Rachel (Mina Kunis Mila Kunis), a beautiful, passionate resort attendant who is willing to listen to his misfortune and takes him into a hot life in Hawaii. Pete falls in love with Rachel, but Sarah breaks up with her new boyfriend and seems willing to turn back to Pete.