After the end of the Cold War, the Bureau of Heavenly Control is in danger of being disbanded, but the largest secret service in the United States still has an important mission. However, recently, the headquarters of the Bureau of Space Control has suffered a sudden attack, resulting in the risk of agents being exposed. It also includes the strong and skillful Agent No. 23 (Dawn Johnson Dwayne Johnson). Headquarters after research found that the attack is a group called the Gaibada Group, in order to meet the enemy, the headquarters entrusted to the analyst Maxwell (Steve Carrell Steve Carell), the latter finally got a chance to show their skills. As a result, he actively participated in the operation against Gebada, but he screwed up the previous two exercises. The only gain is that he partnered with Agent 99 (Anne Hathaway Anne Hathaway), the only agent who is not afraid of identity exposure. They met a suspected terrorist on the plane, but when they shot, they accidentally fell into each other's trap. Since then, the happy enemies have encountered a series of ironic difficulties one after another.