Lieutenant Tucker (Dennis Quaid Dennis Quaid) is impulsive and contemptuous of authoritarianism, but he is also the lead pilot of Project Alpha, which develops microaircraft technology. Tucker's drunken behavior led to the angry departure of his journalist girlfriend Lydia (Meg Ryan Meg Ryan), while that day's work also suffered a setback when a group of bandits broke into the research center and tried to take away the microaircraft chip under development. in order to keep the chip, the researchers injected the miniature Tucker and the aircraft into the ass of a passer-by Jack (Martin short Martin Short). Jack is a nervous supermarket cashier. Tucker wandered inside Jack's body to help him escape the bandits and return to the research center for help. however, the center decided to give up Tucker in Jack for profit, and the two had no choice but to save themselves. they asked Lydia for help, trying to recover the stolen chip before Tucker's oxygen was exhausted, so that Tucker could restore its original size.