Vampire Lestat (Stuart Townsend Stuart Townsend) awakens from his long sleep, he is not willing to go dark, so he is exposed to the public to become a rock singer, an accident Lestat saved the librarian Jesse Reeves (Margaret Morrow Marguerite Moreau), his identity was discovered by Jesse. Lestat uses his song to awaken the legendary vampire queen Akasha (Aria Aaliyah), who sleeps for a thousand years. Akasha and Lestat launch a plan of revenge against their old enemies, but he did not expect that Akasha's ultimate goal is to turn the world into purgatory with him and rule all mankind. At the same time, Jesse fell in love with Lestat. What would Lestat choose? Like the Night interview with Vampires, this film is adapted from Anne Rice's best-selling novel series, Vampire Chronicles.