Child therapist Katherine Dean (Jennifer Lopez Jennifer Lopez) works for a medical research institute that studies the brain. Her task is to fall into the dreams of young patients through high-tech means and heal the scars in their young hearts. The police received a report that many young girls were missing in the area. The FBI agent in charge of the case (Vince Vaughn Vince Vaughn) concluded that this was done by a serial pervert killer. After investigation, the police targeted the suspect-Karl Stagg (Vincent de Onofeo Vincent D'Onofrio), but was unable to save the girl he had imprisoned because he was tight-lipped. At this time, the police contacted Catherine, hoping that she could sneak into the prisoner's brain through dreams to find the location of the victim. However, things are far more dangerous than they thought.