Dylan (Mitchell Haseman Michiel Huisman), the hero with a strict routine, has an innate ability to perceive rules. At 02:22 one afternoon, Dylan Branson, an air traffic controller, was paralyzed by a mysterious light that nearly crashed his plane. From then on, he felt the light every day, and gradually found himself in some kind of cycle. By chance, Dylan met Sarah (Teresa Palmer Teresa Palmer) who fell in love at first sight. They chatted and were surprised to find that Sarah was the flight passenger who almost caused a flight accident by Dylan. Coincidentally, they were born on the same day in the same year. As the two get to know each other better, there are more and more coincidences between Dylan and Sarah, with frequent hallucinations and recurring events linking their fate to a murder at New York's Grand Central Station three decades ago. Dylan has been exploring the secrets behind 2:22 and discovering that the murder of three decades ago is about to repeat itself.