After a night of drunkenness, the FBI's forensic psychoanalyst Dr. Jack Gramm (Al Pacino) is taken away from Mei Xiang by a phone call from a murder that bears a striking resemblance to the Seattle murder nine years ago. Jack's psychoanalysis at that time was the key basis for determining the guilt of the suspect Foster. Now the FBI believes that Foster is innocent, and the videotape of the victim before his death personally confirmed that Jack had the wrong person. The real criminal may be at large. When Jack was confused, he received an inexplicable death threat and learned that he had only 88 minutes to live. In the face of all kinds of sudden mysteries and the threat of death, how should Jack deal with it?