At Liverpool Wharf in 1760, the Collins were taking their young Barnabas aboard a ship bound for the New World to expand the Corinthian empire. Sixteen years later, Barnabas (Johnny Depp Johnny Depp) grows up, inherits the family business and owns Collinwood Manor. The witch Angelique (Eva Green Eva Green) throws herself into her arms, while Barnabas is concerned about the kind girl Josette (Bella Heathcote Bella Heathcote) and mercilessly refuses the witch. The witch became exasperated and cast a poison spell on the two men. Josette was destroyed, while Barnabas became an eternal vampire and was sealed in the coffin. Two centuries later, a construction team inadvertently dug up the coffin, and when Barnabas returned to the manor to make a comeback, he found that the Port of Corinth, which once belonged to him, had become the Angel Bay of witches, and the good people had been ruled by her for 200 years. Can Barnabas, a vampire, recapture the family business and smash the witch's lies? At the same time, a young girl who bears an uncanny resemblance to her former lover Josette came to Port Corinth.