The smooth-talking mercenary Wade Wilson (Ryan Reynolds) meets the playful and lovely Vanessa (Morena Bacarin Morena Baccarin), but at the best of his love moments, he is diagnosed with terminal cancer and has little time left in the world. In extreme despair, he accepts an invitation from Francis (Ed Skrein)'s private organization to modify his genes to seek physical mutations. After enduring a series of cruel tortures, Wade finally cured cancer and transformed into an immortal super soldier, but at the cost of losing his human face. The cunning Francis escapes, but Wade cannot face his girlfriend with a scary face. After that, he transformed into a Deadpool and traveled through every dark corner, looking for Ajax...