The film is adapted from the shooting game of the same name in 1993. In 2145, the headquarters of the Mars Fleet received a weak distress signal from the area, where the scientific exploration station was conducting an important experiment in cracking the genetic code. once the area gets out of control, it will undoubtedly cause a catastrophe for all mankind. Special Operations team captain Rebel (Carl Urban Karl Urban) and Petty Officer Saj (Dawn Johnson Dwayne Johnson) quickly landed with six members to rescue the survivors at the base, but when they entered the base, they found that the lab was not only a mess, but also full of monsters. What is even more frightening is that these strange creatures do not come from extraterrestrials, but humans infected by some unknown virus! In the face of the danger of being infected at any time, Saji and his team must use every weapon in their hands to go deep into the center of the laboratory to find out the truth and complete their mission. The only thing RRTSRTS can do is to block the passage to the earth with the immune isolation system, fight back again, use up every ultimate weapon on his body, and wipe out these monsters one by one.