Dr. Richard (Ioan Gruffudd)'s scientific dream is about to come true! He will fly to the center of the cosmic storm and uncover the code of human genes. Accompanying them are project patron Von Dome (Julian McMahon), astronaut Ben Grimm (Michael Chiklis), the doctor's ex-girlfriend Sue Stone (Jessica Alba) and her brother Johnny Stone (Chris Evans). Unexpectedly, when the spacecraft approached the center of the storm, due to a calculation error, the spacecraft was swallowed by cosmic rays! After escaping the disaster and returning to Earth, the team members 'genes were mutated due to the influence of cosmic rays, and they had different super powers. Richard, Sue, Johnny and Ben form the "Fantastic Four", using the superpowers given by cosmic rays to fight the dark forces and help the world. After gaining powers, Dom transformed into Dr. Steel Eye of Destruction and is implementing his evil plan. The Fantastic Four are attacking!