Another Thanksgiving holiday is coming, and the once-bustling college campus suddenly becomes empty. There is a slightly lonely figure hovering around the empty campus. Her name is Justine (Haley Bennett Haley Bennett), who is forced to stay in school because of the high price of air tickets and studies and subsidies. Not long ago, she said goodbye to her beloved boyfriend and even her dorm friends who had promised to accompany her ran home temporarily for the holidays. Justine spent a long time bored, but did not expect that danger was approaching her. Recently, a series of female college students who are addicted to parties have disappeared in Justine's city. Outside, Justine drives to a nearby supermarket for shopping, but she gets into trouble with an unfriendly woman (Ashley Greene Ashley Greene). Justine managed to escape back to the dormitory, but the nightmare began and Thanksgiving was stained with terrible blood.