In order to study the genetic recombination of different species, a biological company sent staff to enter an ecologically protected area illegally, where they will conduct a series of biological genetic experiments. There they caught a giant crocodile as a petri dish to breed a strange snake in the laboratory through the crocodile. However, due to insufficient anesthetic doses, the crocodile woke up in the experiment, and then the laboratory was destroyed by the crazy crocodile, and the strange snake in the laboratory escaped. The town closest to the reserve was almost wiped out because of the two monsters. Fortunately, the town sheriff Reba found a way to destroy the two monsters and prevent them from killing the whole town.