The super virus "Kimela" and antibiotics were stolen by terrorist organization leader Sean Ambrose (Dougray Scott) during transit. Ethan Hunt (Tom Cruise) led his IMF team to accept a CIA mission to retrieve the virus. This time, Ethan Hunt mates with female cat thief Nyah Nordoff-Hall (Thandie Newton), who is Sean Ambrose's ex-girlfriend. While Ethan Hunt gained Nyah's trust, the two also had a secret love affair. However, in order to complete the mission, Ethan Hunt had to arrange for Nyah to return to Sean Ambrose to go undercover. Nyah finally found out the pharmaceutical factory where the virus was located, and Ethan Hunt, who received the intelligence, went to the pharmaceutical factory to prepare to destroy the virus; on the other hand, Sean Ambrose had already realized Nyah's real purpose in returning to him and organized people to wait for Ethan Hunt to walk into the trap at the pharmaceutical factory. In the fierce struggle,...