On a snowy night, the Nightingale train was driving at high speed, with a man collecting vodka, Petey (Steve Zen Steve Zahn), a bespectacled woman, Chloe (Lily Soborsky Leelee Sobieski), a pair of Japanese playing go, and a cat. When arriving at the station, the conductor was smoking outside, and the conductor Miles (Danny Glover Danny Glover) patrolled around and suddenly came from a distance with a strange man holding a box. He wanted to get on the bus but did not have a ticket, and he kept taking medicine. Miles let him get on the bus out of sympathy. After sitting down, he suddenly foamed at the mouth and died. Miles, Pitty and Chloe were surprised to find that there were priceless treasures in the box in the hands of the dead. As a result, the three decided to destroy the body and take the treasure for themselves. People with lust for profit began to compete, during which the intervention of strange old women and police made the process more complicated and confusing. The passengers died one by one, and there was an unknown secret behind this treasure.