Frank Walsh, the manager of a large animal sanctuary, escorts a Greek transport ship full of strange and deadly large animals from the Amazon, including an extremely rare white jaguar. But deadly animals are not the most frightening creatures on board, as is a team planning to smuggle a political assassin, Richard Loffler, to the United States. Loffler then dumped the American police officer in charge of him and released the beast in the cage, plunging the whole ship into panic and chaos. Frank must find ways to keep the crew safe without harming animals and beware of crazy killers.