There is a secret organization employed by the US government, whose members include leading figures Clay (Jeffrey Dean Morgan Jeffrey Dean Morgan), cynical Jensen (Chris Evans Chris Evans), weapons expert Roque (Idris Elba Idris Elba) and Pucci (Columbus Salt Columbus Short), Kuger (Oscar Jannadah scar Jaenada) and others. When they are on a mission in Bolivia, because of the betrayal of the mole Max (Jason Patrick Jason Patric), everyone's life is shrouded in death threats. Clay took advantage of it, faked everyone's death, renamed "loser" and secretly sneaked back to the United States. At this time, a mysterious girl named Aisha (Zoe Saldana Zoe Saldana) also joins the loser organization and begins to take revenge with Clay and his party. Can Clay and his party successfully catch the mole and regain their dignity? In fact, the secret of the key point lies in Aisha, who is good at kung fu.