There has always been a dark underground world on earth. There, two major races-vampires and werewolves-are fighting to the death, with each side having the ultimate goal of destroying the other. Once, while chasing several defeated werewolves, Silene (Kate Beckinsale), the vampire's "Moon Goddess", discovers that the werewolves are conspiring to kidnap Michael (Scott Speedman), a human doctor. Knowing that the werewolf must have something to do, Silini went to the wolf's den alone to investigate. Unexpectedly, he was ambushed by a werewolf and was rescued by Michael when he was seriously injured. On the way Michael was sending Silene back to the vampire camp, he was accidentally bitten by a vampire, which revealed the mystery of Michael's life and the werewolf plot...