Clark (Chevy Chevy Chase) takes his wife Allen (Beverly de Angelo Beverly D'Angelo) and a pair of children on a journey to Los Angeles in a van. This trip is a long-awaited trip for Clark, who hopes to improve his relationship with his wife. However, as soon as they arrived in St. Louis, Clark and his party suffered a series of setbacks and failed to do anything they wanted to do. not only that, the eccentric and maverick Aunt Edna (Imogen Corka Imogene Coca) joined the family halfway along the way with her grumpy pet dog. It never rains but it pours. Aunt Edna and her dog died one after another. They had to send their aunt's body to her son Nomi, but it was not as simple as they thought.