Tianma Kenzo, a Japanese who works at Eisler Memorial Hospital in West Germany, is known as a "genius doctor". His surgical skills are superb and modest, and he is envied by colleagues and respected by doctors and patients. In career, Tianma has a bright future, which is favored by the dean; in love, the dean's daughter, Eva, is in love with him. However, it seems that all the beautiful Tianma gradually felt uneasy on his conscience. he witnessed that the hospital ignored the dying ordinary people in order to save important people. Tianma suffered a lot from the blame and crying of the family of the deceased. When this dilemma came again, Tenma resolutely chose to save a boy who had been shot in the head. He sacrificed his career and love for the resurrection of a terrible monster. In the following years, Tenma and the monster John launched a game of wits, and a dusty history was slowly uncovered. This film is based on the original work of the same name by Japanese cartoonist Naoki Urazawa.