The battle between werewolves and vampires continues. While Michael (Scott Speedman) and Silene (Kate Beckinsale) are still trying to stop the war with their weak abilities, the conspirators 'masterpiece is born again-a super-powerful race of werewolves and vampires-the "Blood Breeds". Marx (Tony Curran) is the second generation of this race. He killed his father, seized the key and Silene's memories, rescued his twin brothers, one of whom was a werewolf and the other a vampire, who had been imprisoned for thousands of years, in an attempt to unify the three major races of werewolves, vampires and humans. For love, Michael and Silene, the lovers, must defeat Marx's plot and defeat their twin brothers who have been imprisoned for thousands of years...