The cat on the highway comes from a proverb used to describe things that are not destined to last. Giovanni (Antonio Albanese Antonio Albanese) is a typical intellectual who reads books and newspapers every day and thinks carefully about life. He always believes that people can have real trust and integrate with each other. Monica (Paula Cotracy Paola Cortellesi) is the opposite of Giovanni. As a supermarket cashier, she has to deal with guests of different colors and races every day, often feeling anxious and pessimistic about communication between people. God made a little joke that the two people who could not match each other, their children were brought together on a red line, and the two who learned that the relationship sincerely hoped that it would end as soon as possible, like a cat on the highway.