The Egyptian city of Hamnata is the cemetery of pharaohs of past dynasties. It is said that this place contains a large number of rare treasures left by pharaohs. A steady stream of people went to dig gold, but few survived. As a result, Hamnata became a mystery and was named the "City of the Dead". Librarian Evelyn (Rachel Weisz) accidentally gets a map of Hamnata. She is so excited that she decides to go there with her brother for archaeology. They find the former survivor O'Connor (Brendan Fraser), and the three go together. After a thrilling journey, Evelyn and others finally arrived at Hamnata, but the most horrific thing happened: 3,000 years ago, Imhotep, the high priest of Saiti I, committed a crime and was made into a mummy and sealed in a sarcophagus. However, his soul was accidentally awakened. Imhotep, who had incomparable power, was about to wash Egypt with blood, bringing endless disaster to the world...