This family has a pair of parents, twelve children and a bunch of pets. The lively and chaotic situation actually adds happiness to the family. Especially those children with different personalities and ages are as happy as their parents. Now, the family is facing unprecedented changes: because their father Tom (Steve Martin) is going to teach on a college team in a big city, they are moving there, which means that the children will have a better education and a broader space for development; of course, parents 'increasingly busy work will also reduce the time they spend communicating with their children. Her mother, Kate (Bonnie Hunt), has a career as a writer, and she even has to leave home to promote her new book. The children have become increasingly estranged from their parents. Life in a big city has given the family an increasingly glamorous status, but it has lost its inner emotional bonds. It seems that Tom and Kate will have to rethink and make a choice.