In the deep and vast outer space, the blue earth contrasts sharply with the bottomless and pitch-black universe. On a space station belonging to the United States, several astronauts are conducting a spacewalk and conducting routine inspections of their satellites. Dr. Ryan Stone (Sandra Bullock), who has just entered space, methodically inspects every component with the assistance of experienced astronaut Matt Kowalski (George Clooney). This was Koworsky's last flight before retirement, and he animated the atmosphere of the team humorously. At this time, shocking news came from the Houston headquarters. Not long ago, a Russian satellite that was about to be abandoned was destroyed by a missile. The debris scattered in Earth orbit at a speed faster than a bullet and accidentally hit other satellites, causing a chain reaction and creating new debris. Ryan and her party were severely injured by debris, and some of their companions died unfortunately. She and Koworsky lost control and fell deep into the universe. The surviving two had to trust each other and do their best to move towards their homeland...